In line with equities, the rupee today fell by 11 paise to close at 66.44 on fresh demand for the US currency from banks and importers despite weaker dollar in the overseas market.
Fresh foreign capital outflows also affected the rupee sentiment, a forex dealer said.
The rupee resumed lower at 66.41 as against last Friday's level of 66.33 per dollar at the Interbank Foreign Exchange market and hovered in a range of 66.3150 and 66.4550 before ending at 66.44, showing a loss of 11 paise or 0.17%.
The rupee had gained by 19 paise or 0.29% on last Friday.
The dollar index was down 0.19% against a basket of six global currencies in the afternoon.
The RBI fixed the reference rate for the dollar at 66.3435 and euro at 76.0562.
In cross-currency trades, the rupee dropped further against the pound sterling to finish at 97.31 from the last Friday's closing level of 97.05.
It also moved down further against the euro to 76.28 per euro from 75.60 per euro previously.
The domestic currency also dropped further against the yen to 62.20 per 100 yens from 61.92.